Prediction engines really have come on from the early days. Once upon a time there was a plethora of software designed to "crack" rng's.
With the introduction of the online Live Wheel, some software claim to take advantage of the bias play produced by a physical wheel and live dealer. Although "dealer signatures" is a much overused phrase, surely if data can be collected accurately the phenominom could be harvested. Most of us have heard of the success of Biased wheels Section betting (if not try searching Wikipedia for roulette). Anyway a modern take on an old strategy is to employ prediction engines to do the hard work. I believe the user of the other main roulette forums have done a lot of work with this technology and have claimed to significantly better the out of the box hit rate.

Anyway, time will tell if these are the "real thing" or just another scam.